Introduction of PI
Dr. Zhijun Zhang, her research has been mainly focusing on the study of pathogenesis and psychopharmacology of schizophrenia (SCH, particularly from 1995 to 2004). Her team has made substantial improvement in pathology, pharmacogenetics and neuroimaging for schizophrenia. In the past 18 years, her research filed has been expanding to the study of pathogenesis, prevention and treatment of major depression (MD) and amnestic mild cognitive impairment (aMCI)/Alzheimer’s disease (AD) through clinical patients and animal model as well. Up to now, they have made contribution on the investigation of biomarkers for the prediction of early-stage AD and prevention of MD and AD. Most recently, her team focuses on the MD study, especially on developing novel biomarkers and applying multidisciplinary approach to intervene the disease. As the principal investigator, she has been funded with 30 important research projects, published more than 400 peer-reviewed papers including 280 SCI articles. She has been working as chair professor and director of department in Department of Neurology, Affiliated Zhongda Hospital, Research Institution of Neuropsychiatry, School of Medicine, Southeast University from May 2004 to now. She has worked as a visiting scientist in Department of Biomedical Science, Neurocognition and Neuroimaging Research Center, University of Sheffield, U.K, and Department of Psychiatry and Neuroscience Research Center, Belfast University, UK, from July 2000 to December 2006. She has worked in the Department of Biomedical Science, University of Sheffield, UK as a Post-doctoral Research Assistant from March 1999 to February 2000 so on. She has worked in the Department of Psychiatry of Nanjing Brain Hospital as a vice Professor, Professor from March 2000 to May 2004. She has worked in the Neurology Department of Affiliated ZhongDa Hospital of Southeast University as a resident clinical doctor and progressed to a senior resident doctor and then clinical lecturer and senior lecturer of neurology form July 1986 to November 1995.
Research Area
The precise diagnosis and treatment for depressive disorder: screening and functional verification of biomarkers of multiple dimensions and multi-omics, targeting molecule intervention and neuroregulation.
